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Introduction: Benign prostatic hypertrophy (BPH) is a significant contributor of obstructive voiding symptoms in men. Holmium laser enucleation of the prostate (HoLEP) is an effective management option for patients who have failed medical treatment. The purpose of this study is to determine the relationship between prostate volume and postoperative outcomes including postvoid residual, peak voiding flow, and AUA symptoms score of the HoLEP procedure.
Materials & Methods: A retrospective chart review was performed on 72 patients who have undergone the HoLEP procedure from January 2012 to February 2015. Prostate size was measured by transrectal ultrasound. The data was divided into two groups at the median prostate size. Preoperative and postoperative post-void residual volume (PVR), peak voiding flow (PF), and AUA symptom score (AUASS) were measured and compared in each group using paired Student’s t-tests.
Results: The median prostate size was 79 g (range: 17-237g). In the smaller prostate group, PVR was significantly decreased by a mean of 199mL (p<0.001), peak flow was significantly increased by a mean of 11mL/s (p<0.05) and AUASS was significantly decreased by a mean of 12 (p<0.001). In the larger prostate group PVR was significantly decreased by a mean of 113mL (p<0.05), and peak flow was significantly increased by a mean of 8mL/s (p<0.005). There is no significant difference between both groups.
Conclusions: HoLEP is a very effective method of treating BPH in terms of improving symptoms and postoperative outcomes irregardless of prostate size.